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KMID : 0032220090210020171
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Annals of Dermatology
2009 Volume.21 No. 2 p.171 ~ p.173
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Giant Acral Melanoma on the Left Thumb of a Korean Patient
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Kim Jae-Hwan
Jeong Se-Yeong
Shin Jae-Bin
Ro Ki-Woong
Seo Soo-Hong
Son Sang-Wook
Kim Il-Hwan
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Abstract
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The acral regions of the limbs of Asians are predisposed to develop malignant melanoma, but giant-sized acral melanoma has not been previously reported in the Asian population. Giant-sized melanoma implies aggressive tumor invasion and so it is more difficult to achieve a therapeutic cure. A 56-year-old woman presented with a giant acral melanoma of the left thumb with concomitant bone destruction and axillary lymph node metastasis. The initial lesion was a subungual black macule on the left thumb that had grown into a giant 7.0*4.0*3.5 cm-sized melanoma over a 3 year period. The left thumb was amputated and the axillary lymph nodes were completely dissected. During the ensuing 3 months, she underwent adjuvant treatment with interferon-alpha-2a. The interesting feature of this case is that the large melanoma mass of this patient, which was accompanied with adjacent bone destruction and lymph node metastasis, had developed rapidly from a small black macule in the nail matrix, and this black macule was suspected to be a subungual melanoma.
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KEYWORD
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Bone invasion, Interferon-alpha-2a, Lymph node metastasis, Melanoma
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